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KMID : 0371620080230020145
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Journal of Wonkwang Medical Science
2008 Volume.23 No. 2 p.145 ~ p.150
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A Case of Proliferative Glomerulonephritis with Monoclonal IgG Deposits
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Cha Jung-Min
Jung Duk-Eun
Song Ju-Hung
Ahn Seon-Ho
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Abstract
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Proliferative glomerulonephritis with monoclonal IgG deposits is a novel phenotype of glomerular injury with the diagnostic criteria of (1) the presence of glomerular monoclonal IgG deposits restricted to a single IgG subclass and a single light chain isotype, associated with endocapillary proliferative, membranoproliferative, or membranous features; (2) the presence of granular("immune complex type") deposits by electron microscopy; and (3) the absence of clinical and laboratory evidence of cryoglobulinemia. We report a case of 65-year-old man with generalized edema who was diagnosed as proliferative glomerulonephritis with monoclonal IgG deposits by renal biopsy.
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KEYWORD
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monoclonal gammopathy, glomerulonephritis, immunofluorescence
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